منابع مشابه
A cell cycle hypothesis of cooperative oncogenesis (Review).
The development of cancer is a multistep process. To understand oncogenesis and adapt appropriate treatments it is important to have a better definition of a number of factors, including the number and order of oncogenic steps, the identity of the targeted cells and deregulated cellular components, and the genes and pathways altered at each step. We propose here a hypothesis of oncogenesis base...
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III. Cyclins and the cell cycle . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64 A. Major players in cell cycle control . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 64 B. H u m a n cyclins . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ....
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Thyroid neoplasms encompass a variety of lesions that range from benign adenomas to malignancies. These latter can be well-differentiated, poorly differentiated or undifferentiated (anaplastic) carcinomas. More than 95% of thyroid cancers are derived from thyroid follicular cells, while 2-3% (medullary thyroid cancers, MTC) originate from calcitonin producing C-cells. Over the last decade, inve...
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and is characterized by lymphoid infiltration in the periph eral nerves and development of lymphoid tumors in the visceral organs, muscle, and skin. The lymphoma appears to be multifocal and affects the ovary, testes, kidney, liver, lung, and heart. The incidence of lymphoma in the ovary seems to be higher than in the other organs. The disease is highly contagious and affects chickens of all ag...
متن کاملOral Oncogenesis and Chemoprevention
Despite considerable progress in the prevention, detection, and treatment of several cancers, most oral squamous cell carcinomas are detected in the advanced stages. In addition, the multistep process of oral oncogenesis involving accumulation of genetic alterations is complex and not yet fully understood. This short review focuses the current understanding oral oncogenesis, biomarkers, chemopr...
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ژورنال
عنوان ژورنال: Blood
سال: 1967
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v30.3.388.388